University of Benin

PCO 422

Practice 412+ past questions for PCO 422 at University of Benin. Organized by topic with explanations. Free preview on Testwiz.

412+ questions53 topics400 LevelTheory questionsTopic summaries

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About PCO 422 at University of Benin

PCO 422 is a 400 Level course at University of Benin. Students preparing for PCO 422 exams on Testwiz get 412+ practice questions across 53 topics, including theory questions and topic summaries.

Instead of cramming the night before, students who practice by topic — GABA and NMDA in Sleep and ARAS, Antiepileptic Drug Classification by Mechanism, Sodium Channel Blockers in Epilepsy, and more — build real familiarity with how University of Benin tests PCO 422, catch weak spots early with Testwiz's analytics, and walk into the exam with actual reps under their belt.

Topics covered

GABA and NMDA in Sleep and ARASAntiepileptic Drug Classification by MechanismSodium Channel Blockers in EpilepsyCalcium Channel Blockers for SeizuresGlutamate Reduction via NMDA AntagonismACh Role in Huntington's and Alzheimer'sAnticonvulsants as Mood StabilizersBarbiturate Adverse Effects and SafetyBenzodiazepines in Anesthesia and Status EpilepticusInhalational Anesthetic PharmacokineticsHalogenated Hydrocarbon Anesthetic ExamplesGABA Potentiation and Allosteric Binding+41 more

Sample questions

1. Which of the following BEST describes the role of the ascending reticular activating system (ARAS) in the context of sleep and wakefulness?

a.It is a centre that promotes arousal by inhibiting GABAergic neurons in the thalamus.

b.It is a sleep-promoting centre that is activated by NMDA receptor stimulation.

c.It is a centre responsible for generating slow-wave sleep via glutamate release.

d.It is a wakefulness centre that is suppressed by increased GABAergic transmission.

2. A drug that potentiates GABA by binding to an allosteric site on the GABAA receptor is classified as which of the following?

a.A drug that modulates the inhibitory effect of GABA by inhibiting its reuptake.

b.A drug that blocks voltage-gated sodium channels in a use-dependent manner.

c.A drug that reduces the action of glutamate by antagonising NMDA receptors.

d.A drug that binds to the allosteric sites of GABA, such as benzodiazepines.

3. Which of the following statements about sodium channel blockers in epilepsy is TRUE?

a.They are most effective against absence seizures due to their action on T-type calcium channels.

b.They potentiate GABA by binding to the benzodiazepine site on the GABAA receptor.

c.They block sodium channels only when the channels are in the resting closed state.

d.They block sodium channels on a use-dependent basis, entering the channel from behind.

4. A patient with partial epilepsy is prescribed a drug that reduces excitatory neurotransmission by blocking a specific calcium channel. Which of the following drugs is MOST likely being used?

a.Carbamazepine, which blocks sodium channels.

b.Gabapentin, which is a structural analogue of GABA.

c.Vigabatrin, which inhibits GABA transaminase.

d.Felbamate, which antagonises NMDA receptors.

5. Which of the following drugs reduces the action of glutamate by antagonising NMDA receptors?

a.Felbamate

b.Ethosuximide

c.Tiagabine

d.Topiramate

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Testwiz has 412+ PCO 422 practice questions for University of Benin, organized across 53 topics, including theory questions. Sign up free to start practicing.

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What topics does PCO 422 cover on Testwiz?

PCO 422 on Testwiz covers GABA and NMDA in Sleep and ARAS, Antiepileptic Drug Classification by Mechanism, Sodium Channel Blockers in Epilepsy, and more. Practice on Testwiz to see the full topic breakdown and sample questions.